The Diabetic Neuropathies: Practical and Rational Therapy

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The diabetic neuropathies: practical and rational therapy.

Diabetes is associated with a variety of chronic and acute neuropathies. In this article, the authors summarize the clinical features of the most common diabetic neuropathies, focusing on those for which therapy is available or under active investigation. Distal symmetric polyneuropathy (DSP) is the most common form. Potential treatments for DSP are discussed in four broad themes: (1) medicatio...

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Diabetic neuropathy is the most common neuropathy in industrialized countries, with a remarkable range of clinical manifestations. The vast majority of the patients with clinical diabetic neuropathy have a distal symmetrical form that progress following a fiber-length dependent pattern, with predominant sensory and autonomic manifestations. This pattern of neuropathy is associated with a progre...

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INTRODUCTION Changes in human behaviour and lifestyle over the last century have resulted in a dramatic increase in the incidence of diabetes worldwide. Neuropathy is a common and costly complication of both type 1 and type 2 diabetes. The prevalence of neuropathy is estimated to be about 8% in newly diagnosed patients and greater than 50% in patients with long-standing disease. There are two m...

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The diabetic neuropathies: types, diagnosis and management.

Although over the years the considerable breakthroughs made in our understanding of diabetic neuropathy has come from both neurologists and diabetologists, in recent times (in the UK) it is diabetologists that have assumed the main clinical role in diagnosing and managing the most common neuropathy in the western world. It may therefore be that referral of patients with diabetic neuropathy from...

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ژورنال

عنوان ژورنال: Seminars in Neurology

سال: 2012

ISSN: 0271-8235,1098-9021

DOI: 10.1055/s-0032-1329195